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Mca-YVADAPK(Dnp)-OH

Substrate for caspase-1 and -4
 
ALX-260-023-M001 1 mg 302.00 USD
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Specific, highly fluorescent substrate for caspase-1. Also substrate for caspase-4.

Product Specification

Alternative Name:Caspase-1 substrate (fluorogenic)
 
Sequence:Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH (Mca = (7-Methoxycoumarin-4-yl)acetyl; Dnp = Dinitrophenyl)
 
Formula:C53H64N10O19
 
MW:1145.1
 
Purity:≥97% (HPLC)
 
Appearance:White to yellow powder.
 
Solubility:Soluble in DMSO or 80% acetic acid (1mg/ml, with agitation).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C.
 
Technical Info/Product Notes:Mca has an excitation maximum of 325nm and an emission maximum of 392nm.
 

Product Literature References

Sequential activation of ICE-like and CPP32-like proteases during Fas- mediated apoptosis: M. Enari, et al.; Nature 380, 723 (1996), Abstract;

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For Research Use Only. Not for use in diagnostic procedures.
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