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United States 

CA-074

Cathepsin B inhibitor
 
ALX-260-017-M001 1 mg 336.00 USD
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Replaces Prod. #: BML-PI131

Potent and specific inhibitor of cathepsin B in vitro and in vivo. Free acid form used in vitro or in isolated enzyme studies but not in whole cells. Can discriminate between cathepsin B and L/S forms.

Product Specification

Alternative Name:N-[L-3-trans-Propylcarbamoyloxirane-2-carbonyl]-Ile-Pro-OH
 
Formula:C18H29N3O6
 
MW:383.5
 
CAS:134448-10-5
 
Purity:≥98% (HPLC)
 
Appearance:White to off-white powder.
 
Solubility:Soluble in ethyl acetate (50mg/ml) or DMSO.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
260-017
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260-017

Product Literature References

Fluorometric microassays for the determination of cathepsin L and cathepsin S activities in tissue extracts: B. Werle, et al.; Biol. Chem. 380, 1109 (1999), Abstract;
Specific assay method for the activities of cathepsin L-type cysteine proteinases: T. Inubushi, et al.; J. Biochem. 116, 282 (1994), Abstract;
Novel epoxysuccinyl peptides. A selective inhibitor of cathepsin B, in vivo: T. Towatari, et al.; FEBS Lett. 280, 311 (1991), Abstract;
Novel epoxysuccinyl peptides. Selective inhibitors of cathepsin B, in vitro: M. Murata, et al.; FEBS Lett. 280, 307 (1991), Abstract;

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