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Ac-YVAD-2,6-dimethylbenzoyloxymethylketone

Inhibitor of caspase-1 and -4
 
ALX-260-016-M001 1 mg 94.00 USD
 
ALX-260-016-M005 5 mg 360.00 USD
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Irreversible, cell permeable inhibitor of caspase-1. Also inhibits caspase-4.

Product Specification

Alternative Name:Caspase-1 inhibitor, Ac-Tyr-Val-Ala-Asp-2,6-dimethylbenzoyloxymethylketone
 
Sequence:Ac-Tyr-Val-Ala-Asp-2,6-dimethylbenzoyloxymethylketone
 
Formula:C33H42N4O10
 
MW:654.7
 
Peptide Content:78-99%
 
Purity:≥95% (HPLC)
 
Appearance:White powder.
 
Solubility:Soluble in DMSO or methanol.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Use/Stability:Stock solutions should be divided into aliquots and stored at -20°C.
 
Handling:Keep cool and dry.
 

Product Literature References

Ecto-ATPase CD39 Inactivates Isoprenoid-Derived Vγ9Vδ2 T Cell Phosphoantigens: G. Gruenbacher, et al.; Cell Rep. 16, 30728 (2016), Application(s): Bioactivity and cell analysis, Abstract;
Inactivation of interleukin-1 beta converting enzyme by peptide (acyloxy)methyl ketones: N.A. Thornberry, et al.; Biochemistry 33, 3934 (1994), Abstract;

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