Competitive inhibitor of human serum aminopeptidase A, pig kidney leucine aminopeptidase, leucine aminopeptidase, tyrosine aminopeptidase, but not of aminopeptidase B. Has been used to potentiate the action of some bioactive peptides by inhibiting their degradation by aminopeptidases.
Product Specification
| Alternative Name: | [(2S,3R)-3-Amino-2-hydroxy-5-methyl-hexanoyl]-Val-Val-Asp-OH . HCl |
| |
| Formula: | C21H38N4O8 . HCl |
| |
| MW: | 474.6 . 36.5 |
| |
| Source: | Synthetic. |
| |
| CAS: | 100938-10-1 |
| |
| Purity: | ≥98% (HPLC) |
| |
| Appearance: | White to off-white powder. |
| |
| Solubility: | Soluble in acetic acid. |
| |
| Shipping: | Ambient |
| |
| Long Term Storage: | -20°C |
| |
Please mouse over
Product Literature References
Inhibition of aminopeptidases by amastatin and bestatin derivatives. Effect of inhibitor structure on slow-binding processes: D.H. Rich, et al.; J. Med. Chem.
27, 417 (1984),
Abstract;
H. Tobe, et al.; Agric. Biol. Chem. 43, 591 (1979),
Amastatin, an inhibitor of aminopeptidase A, produced by actinomycetes: T. Aoyagi, et al.; J. Antibiot. (Tokyo)
31, 636 (1978),
Abstract;
