HERG2, pAb



ALX-215-052-R100	100 µl	176.00 USD

Product Specification

Alternative Name:	Ether-a-go-go related protein 2, KCNH6, Voltage-gated potassium channel subfamily H member 6, Voltage-gated potassium channel Kv11.2, Erg2

Purity Detail:	Protein A-affinity purified.

Formulation:	Liquid. In 100mM TRIS containing 100mM glycine.

Immunogen:	Recombinant human HERG2 (ether-a-go-go related protein 2) (aa 907-986).

Source/Host:	From rabbit.

Specificity:	Recognizes HERG2 and mouse Erg2.

Application:	Immunocytochemistry (1:50-1:200) Immunohistochemistry (frozen sections, paraffin sections) (1:100-1:400)

Short Term Storage:	-20°C

Long Term Storage:	-80°C

Handling:	After opening, prepare aliquots and store at -80°C. Avoid freeze/thaw cycles.

Miscellaneous/General:	The ether-a-go-go related gene family of K⁺ channels (HERG/Erg) comprises three members, HERG1/Erg1, HERG2/Erg2, HERG3/Erg3. HERG channel activity is relevant to tumor cell biology. It controls cell proliferation, especially in leukaemias. HERG channels are thus considered diagnostic and prognostic factors in human cancers, as well as targets for anti-neoplastic therapies.

Product Literature References

Expression pattern of the ether-a-go-go-related (ERG) family proteins in the adult mouse central nervous system: evidence for coassembly of different subunits: L. Guasti, et al.; J. Comp. Neurol. 491, 157 (2005), Abstract;

Interneurons transiently express the ERG K+ channels during development of mouse spinal networks in vitro: F. Furlan, et al.; Neuroscience 135, 1179 (2005), Abstract;