Product Specification
| Alternative Name: | Interleukin-34 |
| |
| Concentration: | 1mg/ml |
| |
| Purity Detail: | Protein A-affinity purified. |
| |
| Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
| |
| Immunogen: | Recombinant human IL-34 (aa 21-242). |
| |
| Source/Host: | From rabbit. |
| |
| Specificity: | Recognizes human IL-34. |
| |
| Application: | ELISA Western Blot (1:1’000) |
| |
| Short Term Storage: | +4°C |
| |
| Long Term Storage: | -20°C |
| |
| Use/Stability: | Stable for at least 1 year after receipt when stored at -20°C. |
| |
| Handling: | After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. |
| |
| Miscellaneous/General: | IL-34 is a secreted cytokine of 242 aa that promotes the differentiation and viability of monocytes and macrophages. Addition of IL-34 triggers the phosphorylation of ERK1/2. IL-34 binds to colony-stimulating factor-1 receptor CSF1R. |
| |
General Literature References
Discovery of a cytokine and its receptor by functional screening of the extracellular proteome: H. Lin, et al.; Science
320, 807 (2008),
Abstract;