ZBP1 (mouse), pAb (AT132)

Alternative Name:	DAI, DNA-dependent activator of IFN-regulatory factors, Z-DNA-binding protein 1, Tumor stroma and activated macrophage protein DLM-1

Concentration:	1mg/ml

Purity Detail:	Protein A-affinity purified.

Formulation:	Liquid. In PBS containing 0.02% sodium azide.

Immunogen:	Recombinant mouse ZBP1 (aa 1-411) fused to a N-terminal tag.

Source/Host:	From rabbit.

Specificity:	Recognizes mouse ZBP1.

Application:	Immunoprecipitation (1:200) Western blot (1:1’000)

Short Term Storage:	+4°C

Long Term Storage:	-20°C

Handling:	Avoid freeze/thaw cycles.

Miscellaneous/General:	ZBP1 is a cytoplasmic recognition receptor that senses and is activated by DNA from several sources. Upon activation, ZBP1 triggers a type I IFN response through the activation of IRF3 and, probably, IRF7.