| ALX-210-956-C100 | 100 µg | 481.00 USD |  |
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| Alternative Name: | Cig5, RSAD2, Cytomegalovirus-induced gene 5 protein, Radical S-adenosyl methionine domain-containing protein 2, Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to aa near the C-terminus of human viperin. |
| UniProt ID: | Q8WXG1 |
| Source: | Purified from rabbit serum. |
| Species reactivity: | Human, Mouse |
| Applications: | IP, WB |
| Recommended Dilutions/Conditions: | Immunoprecipitation (1:200) Western blot (1:1,000) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Purity Detail: | Epitope-affinity purified. |
| Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
| Handling: | Avoid freeze/thaw cycles. |
| Shipping: | Blue Ice |
| Short Term Storage: | +4°C |
| Long Term Storage: | -20°C |
| Scientific Background: | Viperin has been identified as a human cytomegalovirus and IFN-γ inducible protein. Its expression is activated by both TLR3-dependent and RIG-I-dependent pathways. Viperin inhibits influenza A virus release of infected cells by altering plasma membrane fluidity and the formation of lipid rafts. It acts on the lipid rafts by decreasing the activity of the enzyme farnesyl diphosphate synthase (FPPS) which is essential for isoprenoid biosynthesis. |
| Regulatory Status: | RUO - Research Use Only |
