Omentin 1, pAb (AT117)



ALX-210-941-C100	100 µg	260.00 USD

Product Specification

Alternative Name:	Endothelial lectin HL-1, Intelectin-1, Intestinal lactoferrin receptor, Galactofuranose-binding lectin

Concentration:	1mg/ml

Purity Detail:	Protein A-affinity purified.

Formulation:	Liquid. In PBS containing 0.02% sodium azide.

Immunogen:	Recombinant human omentin 1 (intelectin-1) (aa 17-231).

Source/Host:	From rabbit.

Specificity:	Recognizes human, mouse and rat omentin 1. Cross-reacts with human omentin 2.

Application:	Immunoprecipitation (1:100) Western Blot (1:500)

Short Term Storage:	+4°C

Long Term Storage:	-20°C

Use/Stability:	Stable for at least 1 year after receipt when stored at -20°C.

Handling:	After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.

Crossreactivity Proteins:	Omentin 2

Miscellaneous/General:	Omentin 1 (also named intelectin-1, endothelial lectin HL-1 and intestinal lactoferrin receptor) has been identified as a visceral fat (or omental fat) depot-specific adipokine. Omentin 1 is a secreted protein of ~38 kDa containing a fibrinogen-related domain. Omentin 1 is highly expressed in the omental fat, and much less in intestine, lung and heart. Addition of recombinant omentin in vitro did not affect basal, but enhanced insulin-stimulated glucose uptake in subcutaneous as well as in omental human adipocytes. Omentin 1 triggers AKT signalling in the absence of insulin.

General Literature References

Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action: R.Z. Yang, et al.; Am. J. Physiol. Endocrinol. Metab. 290, E1253 (2006), Abstract;