Voltage-dependent anion channel, pAb



ALX-210-785-C100	100 µg	370.00 USD

Replaces Prod. #: ALX-210-785/1

Product Specification

Alternative Name:	VDAC, Mitochondrial porin

Host:	Rabbit

Immunogen:	Synthetic peptide corresponding to a part (CNDGTEFGGSIYQK) of C-terminal human VDAC (voltage-dependent anion channel) with an added N-terminal cysteine. This sequence is completely conserved between isoforms 1, 2 and 3 of human, mouse and rat VDAC.

UniProt ID:	P21796

Application:	Immunoprecipitation Western Blot (2µg/ml) Optimal conditions must be determined individually for each application.

Specificity:	Recognizes human, mouse, rat and monkey VDAC. Detects a band of ~31kDa by Western blot.

Purity Detail:	Epitope-affinity purified IgG.

Formulation:	Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide.

Handling:	Avoid freeze/thaw cycles.

Long Term Storage:	-20°C

Product Literature References

Synaptic mitochondria are more susceptible to Ca2+overload than nonsynaptic mitochondria: M.R. Brown, et al.; J. Biol. Chem. 281, 11658 (2006), Abstract; Full Text

Modulation of mitochondrial transition pore components by thyroid hormone: E. Yehuda-Shnaidman, et al.; Endocrinology 146, 2462 (2005), Abstract; Full Text

Proteome analysis of DNA damage-induced neuronal death using high throughput mass spectrometry: M.D. Johnson, et al.; J. Biol. Chem. 279, 26685 (2004), Abstract; Full Text

Phospholipid scramblase 3 controls mitochondrial structure, function, and apoptotic response: J. Liu, et al.; Mol. Cancer Res. 1, 892 (2003), Abstract; Full Text

General Literature References

The mitochondrial permeability transition pore and its role in cell death: M. Crompton; Biochem. J. 341 (Pt 2), 233 (1999), Review, Abstract; Full Text