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Voltage-dependent anion channel, pAb

 
ALX-210-785-C100 100 µg 380.00 USD
 
Replaces Prod. #: ALX-210-785/1

Product Specification

Alternative Name:VDAC, Mitochondrial porin
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to a part (CNDGTEFGGSIYQK) of C-terminal human VDAC (voltage-dependent anion channel) with an added N-terminal cysteine. This sequence is completely conserved between isoforms 1, 2 and 3 of human, mouse and rat VDAC.
 
UniProt ID:P21796
 
Species reactivity:Human, Mouse, Rat
Monkey
 
Applications:IP, WB
 
Recommended Dilutions/Conditions:Western Blot (2µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~31kDa by Western blot.
 
Purity Detail:Epitope-affinity purified IgG.
 
Formulation:Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Long Term Storage:-20°C
 

Product Literature References

Synaptic mitochondria are more susceptible to Ca2+overload than nonsynaptic mitochondria: M.R. Brown, et al.; J. Biol. Chem. 281, 11658 (2006), Abstract; Full Text
Modulation of mitochondrial transition pore components by thyroid hormone: E. Yehuda-Shnaidman, et al.; Endocrinology 146, 2462 (2005), Abstract; Full Text
Proteome analysis of DNA damage-induced neuronal death using high throughput mass spectrometry: M.D. Johnson, et al.; J. Biol. Chem. 279, 26685 (2004), Abstract; Full Text
Phospholipid scramblase 3 controls mitochondrial structure, function, and apoptotic response: J. Liu, et al.; Mol. Cancer Res. 1, 892 (2003), Abstract; Full Text

General Literature References

The mitochondrial permeability transition pore and its role in cell death: M. Crompton; Biochem. J. 341 (Pt 2), 233 (1999), Review, Abstract; Full Text

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