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CCR4 (mouse) polyclonal antibody

 
ALX-210-742-R100 100 µl 378.00 USD
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Product Specification

Alternative Name:C-C chemokine receptor 4, CD194
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to aa 8-26 (D8TTQDETVYNSYYFY
ESMP26) of the N-terminal extracellular domain of mouse CCR4 (C-C chemokine receptor 4).
 
UniProt ID:P51680
 
Species reactivity:Mouse
 
Crossreactivity:Does not cross-react with human CCR4.
 
Applications:ICC, IHC (PS), WB
 
Recommended Dilutions/Conditions:Immunocytochemistry (1:500)
Western Blot (1:1,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Epitope-affinity purified F(ab')2 fragment.
 
Quality Control:Immunocytochemistry on mouse spleen cells.
 
Formulation:Liquid. In PBS containing 1mg/ml BSA and 0.1% sodium azide.
 
Handling:For maximum product recovery after thawing, centrifuge the vial before opening the cap. Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Mouse CCR4 is the homolog of human CCR4 receptor (85% identical), binding macrophage inflammatory protein-1α (MIP-1α) and RANTES. Mouse CCR4 transcripts are expressed in the thymus and in T-cell lines.
 

Product Literature References

Dendritic cell immunization route determines CD8+ T cell trafficking to inflamed skin: role for tissue microenvironment and dendritic cells in establishment of T cell-homing subsets: J.C. Dudda, et al.; J. Immunol. 172, 857 (2004), Abstract;

General Literature References

Molecular cloning of murine CC CKR-4 and high affinity binding of chemokines to murine and human CC CKR-4: A. Hoogewerf, et al.; BBRC 218, 337 (1996), Abstract;

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For Research Use Only. Not for use in diagnostic procedures.
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