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UBE1L (human) polyclonal antibody

 
ALX-210-391-R100 100 µl 160.00 USD
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Product Specification

Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to aa 222-240 (D222CDPRSIHVREDGSLEIGD240) of N-terminal human UBE1L.
 
UniProt ID:P41226
 
Species reactivity:Human
 
Applications:IHC (FS), IHC (PS), WB
 
Formulation:Liquid. Raw antiserum. Contains no preservatives.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Human UBE1L shows a 45% homology to the human ubiquitin-activating enzyme E1 at the amino acid level. UBE1L is a retinoid target that triggers promyelocytic leukemia (PML)/ all trans-retinoic acid receptor α (RARα) degradation in acute promyelocytic leukemia.
 

Product Literature References

UBE1L is a retinoid target that triggers PML/RARalpha degradation and apoptosis in acute promyelocytic leukemia: S. Kitareenwan, et al.; PNAS 99, 3806 (2002), Abstract;

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