• Home
  • Contact Us
  • Distributors
  • Support
Toolbar - View Selection
 
Items 1 of 1
ALX-210-352 Revised 01-Feb-10
MDA5 (mouse), pAb (AL180)
Add to Clipboard
SYNONYMS Melanoma differentiation-associated gene 5
Helicard
PRODUCT LINE DNA Regulation / Transcription
PRODUCT CATEGORY RNA Helicases / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
ALX-210-352-C100   100 µg 397.00 USD Add To Cart
Product Specification
SPECIES CROSSREACTIVITY:
Mouse
SOURCE/HOST: From rabbit.
FORMULATION: Liquid. Contains 0.02% sodium azide.
IMMUNOGEN: Recombinant mouse MDA5 (melanoma differentiation-associated gene 5) (aa 2-208).
SPECIFICITY: Recognizes mouse MDA5.
APPLICATION: Western Blot
SHIPPING: SHIPPED ON BLUE ICE
SHORT TERM STORAGE: +4°C
LONG TERM STORAGE: -20°C
USE/STABILITY: Stable for at least 1 year after receipt when stored as recommended.
HANDLING: Avoid freeze/thaw cycles.
Product Specific Literature References
Overexpression of Helicard, a CARD-Containing Helicase Cleaved during Apoptosis, Accelerates DNA Degradation: M. Kovacsovics, et al.; Curr. Biol. 12, 838 (2002) Abstract
General Information
MDA5 is a highly conserved helicase whose ATPase activity can be stimulated by RNA and less potently by DNA. It contains two N-terminal CARD domains and a C-terminal helicase domain. The helicase domain, once freed from the CARD domains, then translocates from the cytoplasm to the nucleus where it acts on chromatin architecture. This could allow a more easy access of CAD, thereby accelerating the degradation of genomic DNA.
General Literature References
Mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties: D.C. Kang, et al.; PNAS 99, 637 (2002) Abstract
Related Products
Further Categories Containing This Product:
Caspase Recruitment Domain [CARD] Proteins / Related Products • Interferons & Interferon Receptors Other Products • Antiviral Signalling / Related Products • NF-kB Pathway Other Products • Polyclonal Antibodies
 
 
© 2009 Enzo Life Sciences, Inc., Privacy, Disclaimer, Terms, Sitemap, Legalanother CS2 website

My Account

Register Login
You are logged on as Guest.

Catalogs / Brochures

E-Newsletter

 

Shopping Cart [0]

Clipboard [0]

Your items will be kept only for the duration of your visit.

Custom Services


Peptide Synthesis
Antibody Production
Protein Expression
Organic Synthesis
Immunoassays

Enzo Life Sciences
incorporating: