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Bax polyclonal antibody

 
ALX-210-003-R050 50 µl 144.00 USD
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Product Specification

Alternative Name:BCL2L4, BCL2-associated X protein
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to aa 43-61 (P43ELTLEQPPQDASTKKLSE61) of mouse Bax. This sequence is completely conserved in rat Bax.
 
UniProt ID:Q07813
 
Species reactivity:Human, Mouse, Rat
 
Applications:IHC (FS), IHC (PS), IP, WB
 
Recommended Dilutions/Conditions:Immunohistochemistry (paraffin sections, 1:500-1:2,000)
Immunoprecipitation (1µl/106 cells)
Western Blot (1:500-1:2,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Formulation:Liquid. In PBS containing 0.05% sodium azide.
 
Use/Stability:Stable for at least 1 year after receipt when stored at -80°C.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 
Long Term Storage:-80°C
 

Product Literature References

The gastroprotective effects of hydroalcoholic extract of Monolluma quadrangula against ethanol-induced gastric mucosal injuries in Sprague Dawley rats: I.A.A. Ibrahim, et al.; Drug Des. Devel. Ther. 10, 93 (2016), Application(s): Western blot, Abstract; Full Text
Mcl-1 is a key regulator of the ovarian reserve: S. Omari, et al.; Cell. Death Dis. 6, e1755 (2015), Application(s): Immunofluorescence, Abstract; Full Text
Sequential cleavage of poly(ADP-ribose)polymerase and appearance of a small Bax-immunoreactive protein are blocked by Bcl-X(L) and caspase inhibitors during staurosporine-induced dopaminergic neuronal apoptosis: J.E. Kim, et al.; J. Neurochem. 72, 2456 (1999), Abstract; Full Text
Bax cleavage is mediated by calpain during drug-induced apoptosis: D.E. Wood, et al.; Oncogene 17, 1069 (1998), Abstract;
Developmental expression patterns of Bcl-2, Bcl-x, Bax, and Bak in teeth: S. Krajewski, et al.; Cell Death Differ. 5, 408 (1998), Abstract;
Apoptosis in the terminal endbud of the murine mammary gland: a mechanism of ductal morphogenesis: R.C. Humphreys, et al.; Development 122, 4013 (1996), Abstract; Full Text
Expression of Bcl-2, Bcl-x, and Bax after T cell activation and IL-2 withdrawal: H.E. Broome, et al.; J. Immunol. 155, 2311 (1995), Abstract;
Overexpression of the Bcl-2 protein increases the half-life of p21Bax: T. Miyashita, et al.; J. Biol. Chem. 270, 26049 (1995), Abstract; Full Text
Upregulation of bax protein levels in neurons following cerebral ischemia: S. Krajewski, et al.; J. Neurosci. 15, 6364 (1995), Abstract;
Immunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of Bcl-2: S. Krajewski, et al.; Am. J. Pathol. 145, 1323 (1994), Abstract;

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