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Angiopoietin-1 (human), (recombinant)

ALX-201-850-0020 20 µg 193.00 USD
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Product Specification

Alternative Name:Ang-1, ANGPT1
Source:Produced in E. coli. Human Ang-1 (angiopoietin-1) is a single, non-glycosylated polypeptide chain containing 480 amino acids (20-498)
UniProt ID:Q15389
Formulation:Liquid. Sterile filtered, in 20mM TRIS-HCl buffer, pH 8.0, 1M urea containing 5% glycerol.
Purity:≥85% (SDS-PAGE)
Appearance:Colorless liquid.
Shipping:Shipped on Blue Ice
Long Term Storage:-20°C
Use/Stability:Store at +4°C if entire vial will be used within 2-4 weeks. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Handling:Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Scientific Background:ANGPT1 is an angiogenic factor which intervenes in blood vessel maturation and takes part in endothelial development. ANGPT1 is a secreted ligand for Tie-2, a cell surface receptor tyrosine kinase expressed in endothelial and hemopoietic cells. The glycosylated ANGPT1 protein has a coiled-coil region in the amino terminus and a fibrinogen-like domain at the carboxy terminus.      

Product Literature References

Dachengqi Decoction Attenuates Intestinal Vascular Endothelial Injury in Severe Acute Pancreatitis in Vitro and in Vivo: L. Y. Pan, et al.; Cell. Physiol. Biochem. 44, 2395 (2017), Abstract; Full Text

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