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TGF-β3 (mouse), (recombinant)

 
ALX-201-817-0010 10 µg 214.00 USD
 
ALX-201-817-0100 100 µg 709.00 USD
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  • High purity
  • Carrier-free

Product Specification

Alternative Name:Transforming growth factor β3
 
MW:~25.5kDa
 
Source:Produced in E. coli. Non-glycosylated, disulfide-linked homodimer, containing two 112 amino acid chains.
 
UniProt ID:P17125
 
Concentration:0.25mg/ml
 
Formulation:Liquid. In 20% ethanol and 0.12% acetic acid.
 
Purity:≥98% (Reducing and Non-reducing SDS-PAGE)
 
Endotoxin Content:≤1 EU/μg protein measured by kinetic LAL analysis.
 
Appearance:Clear solution.
 
Biological Activity:The activity is determined by the cell toxicity assay, using the WHO Standard 98/608 as a direct comparison, which is typically observed at concentations <0.05ng/ml.
 
Shipping:Ambient
 
Long Term Storage:+4°C
 
Use/Stability:Stable at +4°C for 1 year from date of purchase.
 
Scientific Background:The transforming growth factors (TGFs) are multifunctional peptides that regulate growth and differentiation in a variety of cells. Recent data suggests that individual TGF-β isoforms (TGF-β1, -β2 and –β3) have overlapping, yet distinct biological actions and target cell specificities, both in developing and adult tissues. TGF-β3 is a new isoform that is presumed to play an important role in wound repair and scarring. TGF-β3 is also thought to be involved in osteoblast proliferation, chemotaxis, and collagen synthesis.
 

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