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Pro-IL-33 (human), (recombinant) (His-tag)

 
ALX-201-504-0010 10 µg 421.00 USD
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Product Specification

Alternative Name:Interleukin-33, NF-HEV, IL-1F11
 
MW:~30kD
 
Source:Produced in E. coli. The mature domain of recombinant human IL-33 (aa 1-270) is fused at the C-terminus to a His-tag.
 
UniProt ID:O95760
 
Formulation:Liquid. In 100mM sodium phosphate, 500mM sodium chloride, 25mM imidazole, 10% glycerol.
 
Purity:≥95% (SDS-PAGE)
 
Applications:WB
 
Application Notes:Western blot control.
 
Shipping:Shipped on Dry Ice
 
Long Term Storage:-80°C
 
Use/Stability:Working aliquots are stable for up to 3 months when stored at -80°C.
 
Handling:For maximum product recovery after thawing, centrifuge the vial before opening the cap. Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -80°C.
 

General Literature References

The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1: C. Cayrol & J.P. Girard; Proc. Nat.l Acad. Sci. USA 106, 9021 (2009), Abstract; Full Text
IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo: V. Carriere et al.; Proc. Natl. Acad. Sci. USA 104, 282 (2007), Abstract;
IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines: J. Schmitz, et al.; Immunity 23, 479 (2005), Abstract;
Molecular characterization of NF-HEV, a nuclear factor preferentially expressed in human high endothelial venules: E.S. Baekkevold, et al. ; Am. J. Pathol. 163, 69 (2003), Abstract;

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