Product Details
| Alternative Name: | Interleukin-33, NF-HEV, IL-1F11 |
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| MW: | ~30kD |
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| Source: | Produced in E. coli. The mature domain of recombinant human IL-33 (aa 1-270) is fused at the C-terminus to a His-tag. |
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| UniProt ID: | O95760 |
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| Formulation: | Liquid. In 100mM sodium phosphate, 500mM sodium chloride, 25mM imidazole, 10% glycerol. |
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| Purity: | ≥95% (SDS-PAGE) |
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| Applications: | WB
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| Application Notes: | Western blot control. |
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| Shipping: | Dry Ice |
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| Long Term Storage: | -80°C |
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| Use/Stability: | Working aliquots are stable for up to 3 months when stored at -80°C. |
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| Handling: | For maximum product recovery after thawing, centrifuge the vial before opening the cap. Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -80°C. |
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| Regulatory Status: | RUO - Research Use Only |
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General Literature References
The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1: C. Cayrol & J.P. Girard; Proc. Nat.l Acad. Sci. USA
106, 9021 (2009),
Abstract;
Full Text
IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo: V. Carriere et al.; Proc. Natl. Acad. Sci. USA
104, 282 (2007),
Abstract;
IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines: J. Schmitz, et al.; Immunity
23, 479 (2005),
Abstract;
Molecular characterization of NF-HEV, a nuclear factor preferentially expressed in human high endothelial venules: E.S. Baekkevold, et al. ; Am. J. Pathol.
163, 69 (2003),
Abstract;
