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ANGPTL3 (coiled-coil domain) (mouse), (recombinant) (His-tag)

ALX-201-412-C010 10 µg 284.00 USD
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Product Specification

Alternative Name:Angiopoietin-like protein 3, Angiopoietin-5, ANG-5
Source:Produced in HEK 293 cells. The signal peptide and the coiled-coil domain of mouse ANGPTL3 (angiopoietin-like protein 3) (aa 1-206) are fused at the C-terminus to a His-tag.
UniProt ID:Q9R182
Formulation:Liquid. 0.2μm-filtered solution in PBS.
Purity:≥90% (SDS-PAGE)
Endotoxin Content:<1EU/µg protein (LAL-test).
Shipping:Shipped on Blue Ice
Long Term Storage:-20°C
Use/Stability:Working aliquots are stable for up to 3 months when stored at -20°C.
Handling:Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Figure: SDS-PAGE of ANGPTL3 (Coiled-coil Domain) (mouse) (recombinant) (His) (Prod. No. ALX-201-412).
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General Literature References

Angiopoietin-like proteins: potential new targets for metabolic syndrome therapy: Y. Oike, et al.; Trends Mol. Med. 11, 473 (2005), Abstract;
Differential regulation and properties of angiopoietin-like proteins 3 and 4: H. Ge, et al.; J. Lipid Res. 46, 1484 (2005), Abstract;
ANGPTL3 is increased in both insulin-deficient and -resistant diabetic states: K. Inukai; Biochem. Biophys. Res. Commun. 317, 1075 (2004), Abstract;
Angiopoietin-like protein 3, a hepatic secretory factor, activates lipolysis in adipocytes: M. Shimamura, et al. ; Biochem. Biophys. Res. Commun. 301, 604 (2003), Abstract;
ANGPTL3 decreases very low density lipoprotein triglyceride clearance by inhibition of lipoprotein lipase: T. Shimizugawa, et al.; J. Biol. Chem. 27, 33742 (2002), Abstract; Full Text
Identification of a mammalian angiopoietin-related protein expressed specifically in liver: D. Conklin, et al.; Genomics 62, 477 (1999), Abstract;

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