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pro-Bone morphogenetic protein 2 (human), (recombinant)

 
ALX-201-204-C010 10 µg 414.00 USD
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Replaces Prod. #: ALX-201-204/1

Product Specification

Alternative Name:proBMP-2
 
MW:~85.5kDa.
 
Source:Produced in E. coli and renatured from inclusion body material.
 
UniProt ID:P12643
 
Concentration:100μg/ml after reconstitution.
 
Formulation:Lyophilized from 0.1M K-HEPES, pH 7.0, containing 3% mannitol.
 
Purity:≥98% (SDS-PAGE, UV, MS)
 
Endotoxin Content:<0.02EU/mg protein.
 
Biological Activity:Administration leads to ectopic bone formation in rats.
 
Reconstitution:Reconstitute with 100μl distilled water at +4°C for 30 minutes.
 
Shipping:Shipped on Dry Ice
 
Long Term Storage:-80°C
 
Use/Stability:The reconstituted solution can be diluted into other aqueous buffers and stored at +4°C for up to two weeks. Below 10μg/ml, 0.5% BSA or serum should be added.
 
Handling:Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C.
 

Product Literature References

Biophysical comparison of BMP-2, ProBMP-2, and the free pro-peptide reveals stabilization of the pro-peptide by the mature growth factor : F. Hillger, et al.; J. Biol. Chem. 280, 14974 (2005), Abstract; Full Text

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