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Resistin (human), (recombinant)

 
ALX-201-195-C100 100 µg 784.00 USD
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Product Specification

Alternative Name:ADSF, FIZZ3
 
MW:~9.9kDa.
 
Source:Produced in E. coli.
 
UniProt ID:Q9HD89
 
Concentration:0.5mg/ml after reconstitution.
 
Formulation:Lyophilized from 25mM TRIS, pH 7.5, containing 25mM sodium chloride.
 
Purity:≥95% (SDS-PAGE)
 
Applications:ELISA, WB
 
Reconstitution:Reconstitute with 200µl 25mM TRIS, pH 7.5 containing 25mM sodium chloride.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Use/Stability:Reconstituted protein is stable for 4 weeks when stored at 4°C.
 
Handling:Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C.
 
Scientific Background:Resistin (also called adipose tissue-specific secretory factor (ADSF) or found in inflammatory zone 3 (FIZZ3)) is another hormone secreted by adipocytes that acts on skeletal muscle myocytes, hepatocytes and adipocytes themselves, where it is suggested to reduce insulin sensitivity leading to type 2 diabetes.
 
Manufacturer:Manufactured by BioVendor.
 

General Literature References

Mechanisms regulating adipocyte expression of resistin: H.B. Hartman, et al.; J. Biol. Chem. 277, 19754 (2002), Abstract;
Resistin and obesity-associated insulin resistance: C.M. Steppan & M.A. Lazar; Trends Endocrinol. Metab. 13, 18 (2002), Abstract;
A cysteine-rich adipose tissue-specific secretory factor inhibits adipocyte differentiation: K.H. Kim, et al.; J. Biol. Chem. 276, 11252 (2001), Abstract; Full Text
Adipose tissue resistin expression is severely suppressed in obesity and stimulated by peroxisome proliferator-activated receptor gamma agonists: J.M. Way, et al.; J. Biol. Chem. 276, 25651 (2001), Abstract; Full Text
Dimerization of resistin and resistin-like molecules is determined by a single cysteine: R.R. Banerjee & M.A. Lazar; J. Biol. Chem. 276, 25970 (2001), Abstract; Full Text
The hormone resistin links obesity to diabetes: C.M. Steppan, et al.; Nature 409, 307 (2001), Abstract;

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