Resistin (human), (recombinant)



ALX-201-195-C100	100 µg	696.00 USD

Product Specification

Alternative Name:	ADSF, FIZZ3

Concentration:	0.5mg/ml after reconstitution.

MW:	~9.9kDa.

Purity:	≥95% (SDS-PAGE)

Formulation:	Lyophilized from 25mM TRIS, pH 7.5, containing 25mM sodium chloride.

Source/Host:	Produced in E. coli.

Reconstitution:	Reconstitute with 200µl 25mM TRIS, pH 7.5 containing 25mM sodium chloride.

Application:	ELISA Western Blot

Long Term Storage:	-20°C

Use/Stability:	Reconstituted protein is stable for 4 weeks when stored at 4°C.

Handling:	After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.

Miscellaneous/General:	Resistin (also called adipose tissue-specific secretory factor (ADSF) or found in inflammatory zone 3 (FIZZ3)) is another hormone secreted by adipocytes that acts on skeletal muscle myocytes, hepatocytes and adipocytes themselves, where it is suggested to reduce insulin sensitivity leading to type 2 diabetes.

Background / Technical Information:	UniProt ID Q9HD89: Resistin (human)

General Literature References

Mechanisms regulating adipocyte expression of resistin: H.B. Hartman, et al.; J. Biol. Chem. 277, 19754 (2002), Abstract;

Resistin and obesity-associated insulin resistance: C.M. Steppan & M.A. Lazar; Trends Endocrinol. Metab. 13, 18 (2002), Abstract;

A cysteine-rich adipose tissue-specific secretory factor inhibits adipocyte differentiation: K.H. Kim, et al.; J. Biol. Chem. 276, 11252 (2001), Abstract; Full Text

Adipose tissue resistin expression is severely suppressed in obesity and stimulated by peroxisome proliferator-activated receptor gamma agonists: J.M. Way, et al.; J. Biol. Chem. 276, 25651 (2001), Abstract; Full Text

Dimerization of resistin and resistin-like molecules is determined by a single cysteine: R.R. Banerjee & M.A. Lazar; J. Biol. Chem. 276, 25970 (2001), Abstract; Full Text

The hormone resistin links obesity to diabetes: C.M. Steppan, et al.; Nature 409, 307 (2001), Abstract;