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NEDP1 (human), (recombinant)

Deconjugating Enzyme (DCE)
 
ALX-201-171-C050 50 µg 226.00 USD
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Product Specification

Alternative Name:NEDD8-specific protease 1, SENP8, Sentrin-specific protease 8, Deneddylase 1
 
Source:Produced in E. coli.
 
UniProt ID:Q96LD8
 
Concentration:1mg/ml
 
Formulation:Liquid. In 50mM TRIS-HCl, pH 7.5, 100mM sodium azide, 5mM β-mercaptoethanol and 10% glycerol.
 
Shipping:Shipped on Dry Ice
 
Long Term Storage:-80°C
 
Scientific Background:NEDP1 is a highly conserved cysteine protease that deNEDDylates cullins. NEDP1 appears to be specific for NEDD8 as neither ubiquitin nor SUMO C-terminal extensions are utilized as substrates.
 

Product Literature References

NEDP1, a highly conserved cysteine protease that deNEDDylates Cullins: H.M. Mendozy, et al.; J. Biol. Chem. 278, 25637 (2003), Abstract;

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