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Arginase l (human), (recombinant)

 
ALX-201-081-C020 20 µg 377.00 USD
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Product Specification

Alternative Name:ARG1
 
Source:Produced in E. coli. Full length human arginase I.
 
EC:3.5.3.1
 
UniProt ID:P05089
 
Formulation:Liquid. In 10mM TRIS-HCl, pH 7.5, containing 1mM β-mercaptoethanol, 1mM MnCl2 and 50% glycerol.
 
Purity:≥90% (SDS-PAGE)
 
Specific Activity:~2.0U/µg protein. One unit is defined as the amount of enzyme that converts 1µmol of L-arginine to L-ornithine and urea per min. at 37°C, pH 9.5 (R.T. Schminke, et al.; J. Biol. Chem. 238, 1012 (1962)).
 
Shipping:Shipped on Dry Ice
 
Long Term Storage:-80°C
 

Product Literature References

Increased levels of arginase in patients with acute hepatitis B suppress antiviral T cells: E. Sandalova, et al.; Gastroenterology 143, 78 (2012), Abstract;
Biodegradable chitosan particles induce chemokine release and negligible arginase-1 activity compared to IL-4 in murine bone marrow-derived macrophages: J. Guzman-Morales, et al.; BBRC 405, 538 (2011), Abstract;
Short-term correction of arginase deficiency in a neonatal murine model with a helper-dependent adenoviral vector: C.L. Gau, et al.; Mol. Ther. 17, 1155 (2009), Abstract;
Arginase 1 is expressed in myelocytes/metamyelocytes and localized in gelatinase granules of human neutrophils: L.C. Jacobsen, et al.; Blood 109, 3084 (2007), Abstract;
Implications of the S-shaped domain in the quaternary structure of human arginase: A. Mora, et al.; Biochim. Biophys. Acta 1476, 181 (2000), Abstract;
Determination of arginase activity in macrophages: a micromethod: I.M. Corraliza, et al.; J. Immunol. Methods 174, 231 (1994), Abstract;

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