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Proendothelin-1 (human), (recombinant)

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Product Specification

Alternative Name:ProET-1
 
MW:~26kDa.
 
Source:Produced in XL1-Blue cells. Human proendothelin-1 (aa 18-212) is fused to a His-tag. The N-terminal peptide sequence Met-Arg-Gly-Ser-(His)6 replaces the signal peptide.
 
UniProt ID:P25101
 
Formulation:Lyophilized. Contains no preservatives.
 
Purity:≥80% (SDS-PAGE)
 
Biological Activity:4µg (160pmoles) of recombinant human proendothelin-1 when cleaved with furin and chymosin has been shown to produce endothelin-1 mediated vasoconstriction of rat vas deferens and rabbit carotid artery.
 
Reconstitution:Reconstitute in sterile water.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:+4°C
 

Product Literature References

Processing of proendothelin-1 by human furin convertase: J.-B. Denault, et al.; FEBS Lett. 362, 276 (1995), Abstract;

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Endothelin
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Endothelin Recombinant protein
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