Proendothelin-1 (human), (recombinant)

MW:	~26kDa.

Purity:	~80% (SDS-PAGE)

Formulation:	Lyophilized. Contains no preservatives.

Biological Activity:	4µg (160pmoles) of recombinant human proendothelin-1 when cleaved with furin and chymosin has been shown to produce endothelin-1 mediated vasoconstriction of rat vas deferens and rabbit carotid artery.

Source/Host:	Produced in XL1-Blue cells. Human proendothelin-1 (aa 18-212) is fused to a His-tag. The N-terminal peptide sequence Met-Arg-Gly-Ser-(His)₆ replaces the signal peptide.

Reconstitution:	Reconstitute in sterile water.

Long Term Storage:	+4°C

Background / Technical Information:	UniProt ID P25101: Endothelin-1 (human) AfCS Signaling Gateway ID A000062: Endothelin-1 (mouse)