Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Granzyme B (human lymphocytes)

 
ALX-200-602-C010 10 µg 644.00 USD
Do you need bulk/larger quantities?
 

Product Specification

MW:~32kDa.
 
Source:Isolated from YT NK cell line using described methods. Active enzyme.
 
EC:3.4.21.79
 
UniProt ID:P10144
 
Formulation:Liquid. In 150mM sodium chloride. Contains no preservatives.
 
Biological Activity:Using standard cell lines, 1µg/ml is sufficient to kill 1x106 cells when delivered by the appropiate agent.
 
Specific Activity:15U/µg protein. One unit is defined as the amount of enzyme that hydrolyzes 1nmol BAADT per min. (Prod. No. ALX-260-050).
 
Shipping:Shipped on Dry Ice
 
Long Term Storage:-80°C
 
Use/Stability:Do not dilute below 1mg/ml. Dilute solutions should be used within 24 hours.
 
Handling:Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -80°C.
 
200-602 1
200-602 2
Please mouse over
200-602 1 200-602 2

Product Literature References

New paradigm for lymphocyte granule-mediated cytotoxicity. Target cells bind and internalize granzyme B, but an endosomolytic agent is necessary for cytosolic delivery and subsequent apoptosis: C.J. Froelich, et al.; J. Biol. Chem. 271, 29073 (1996), Abstract; Full Text
Rapid purification of cationic granule proteases: application to human granzymes: W.L. Hanna, et al.; Protein Purif. Exp. 4, 398 (1993), Abstract;

Related Products

BAADT 

Granzyme B substrate
≥95% (TLC) | Print as PDF
 
ALX-260-050-M005 5 mg 459.00 USD
Do you need bulk/larger quantities?
 

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
Granzyme
By biological activity:
Granzyme Native protein
Granzyme Enzyme
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,