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H-Trp-Glu-OH

PPARγ antagonist
 
ALX-190-001-M050 50 mg 91.00 USD
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Cell permeable, selective and reversible PPARγ antagonist. Has been shown to inhibit the agonist activity of rosiglitazone (Prod. No. ALX-350-125) in a dose-dependent manner (IC50=31.9µM).

Product Specification

Alternative Name:H-WE-OH, G3335
 
Formula:C16H19N3O5
 
MW:333.3
 
CAS:36099-95-3
 
Purity:≥97%
 
Appearance:White to off-white solid.
 
Solubility:Soluble in water (50mg/ml).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Protect from light.
 

Product Literature References

The nuclear receptor-coactivator interaction surface as a target for peptide antagonists of the peroxisome proliferator activated receptors: N. B. Mettu, et al.; Mol. Endocrinol. 21, 2361 (2007), Abstract; Full Text
The dipeptide H-Trp-Glu-OH shows highly antagonistic activity against PPARgamma: bioassay with molecular modeling simulation: F. Ye, et al.; Chembiochem. 7, 74 (2006), Abstract;

Related Products

Rosiglitazone 

Insulin sensitizing agent
122320-73-4, ≥97% (HPLC) | Print as PDF
 
ALX-350-125-M025 25 mg 114.00 USD
 
ALX-350-125-M100 100 mg 326.00 USD
Do you need bulk/larger quantities?
 

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