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pp60v-src (137-157)

Receptor tyrosine kinase inhibitor
 
ALX-165-004-M001 1 mg 123.00 USD
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Inhibitor of Src and EGF receptor tyrosine kinases. The peptide sequence corresponds to residues 137-157 of the noncatalytic domain of the transforming protein of Rous sarcoma virus (pp60v-src).

Product Specification

Alternative Name:Peptide A
 
Sequence:H-Val-Ala-Pro-Ser-Asp-Ser-Ile-Gln-Ala-Glu-Glu-Trp-Tyr-Phe-Gly-Lys-Ile-Thr-Arg-Arg-Glu-OH
 
Formula:C111H168N30O35
 
MW:2482.7
 
Purity:≥98%
 
Appearance:White lyophilized powder.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 

Product Literature References

Evidence for autoinhibitory regulation of the c-src gene product. A possible interaction between the src homology 2 domain and autophosphorylation site: Y. Fukami, et al.; J. Biol. Chem. 268, 1132 (1993), Abstract; Full Text
A synthetic peptide corresponding to residues 137 to 157 of p60v-src inhibits tyrosine-specific protein kinases: K. Sato, et al.; BBRC 171, 1152 (1990), Abstract;

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