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Nociceptin

ORL1 receptor agonist
 
ALX-163-001-P001 1 mg* 110.00 USD
 
ALX-163-001-P005 5 mg* 345.00 USD
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ORL1 receptor agonist. The ORL1 receptor structurally resembles opioid receptors and is negatively coupled with adenylyl cyclase.

Product Specification

Alternative Name:Orphanin FQ
 
Sequence:H-Phe-Gly-Gly-Phe-Thr-Gly-Ala-Arg-Lys-Ser-Ala-Arg-Lys-Leu-Ala-Asn-Gln-OH
 
Formula:C79H129N27O22
 
MW:1809.1
 
CAS:170713-75-4
 
Quantity:*Sold as net peptide weight
 
Purity:≥97%
 
Appearance:Lyophilized.
 
Solubility:Soluble in water.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 

Product Literature References

Primary structure and tissue distribution of the orphanin FQ precursor: H.-P. Nothacker, et al.; PNAS 93, 8677 (1996), Abstract;
Sensitivity of opioid receptor-like receptor ORL1 for chemical modification on nociceptin, a naturally occurring nociceptive peptide: Y. Shimohigashi, et al.; J. Biol. Chem. 271, 23642 (1996), Abstract; Full Text
Structure-activity relationship studies on the novel neuropeptide orphanin FQ: R.K. Reinscheid, et al.; J. Biol. Chem. 271, 14163 (1996), Abstract; Full Text
Isolation and structure of the endogenous agonist of opioid receptor- like ORL1 receptor: J.-C. Meunier, et al.; Nature 377, 532 (1995), Abstract;
N23K, a gene transiently up-regulated during neural differentiation, encodes a precursor protein for a newly identified neuropeptide nociceptin: Y. Saito, et al.; BBRC 217, 539 (1995), Abstract;
Orphanin FQ: a neuropeptide that activates an opioidlike G protein- coupled receptor: R.K. Reinscheid, et al.; Science 270, 792 (1995), Abstract;

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