Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

MARCKS protein (bovine brain) (151-175)

Excellent PKC substrate
 
ALX-162-004-MC05 0.5 mg 94.00 USD
 
ALX-162-004-M001 1 mg 164.00 USD
Do you need bulk/larger quantities?
 
Replaces Prod. #: BML-P117

Excellent substrate for protein kinase C (PKC) (Km = 20nM for purified rat brain PKC). The peptide consists of residues 151-175 of the myristoylated alanine-rich C-kinase substrate (MARCKS) protein phosphorylation site. Protein kinase C isotypes (including PKCε) phosphorylate serines 8, 12 and 19 of this peptide. It is a very weak substrate for cAMP- and cGMP-dependent protein kinase and CaM kinases I, II and III.

Product Specification

Sequence:H-Lys-Lys-Lys-Lys-Lys-Arg-Phe-Ser-Phe-Lys-Lys-Ser-Phe-Lys-Leu-Ser-Gly-Phe-Ser-Phe-Lys-Lys-Asn-Lys-Lys-OH
 
Formula:C147H243N41O31
 
MW:3081.8
 
CAS:125267-21-2
 
Formulation:Lyophilized
 
Purity:≥98%
 
Appearance:White to off-white powder. 
 
Solubility:Soluble in water.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 

Product Literature References

The MARCKS family of cellular protein kinase C substrates: P.J. Blackshear; J. Biol. Chem. 268, 1501 (1993), (Minireview), Abstract; Full Text
Protein kinase C substrate and inhibitor characteristics of peptides derived from the myristoylated alanine-rich C kinase substrate (MARCKS) protein phosphorylation site domain: J.M. Graff, et al.; J. Biol. Chem. 266, 14390 (1991), Abstract; Full Text

General Literature References

Multisite phosphorylation of the 80 kDa (MARCKS) protein kinase C substrate in C3H/10T1/2 fibroblasts. Quantitative analysis of individual sites by solid-phase microsequencing.: B. Amess et al.; FEBS Lett. 297, 285 (1992), Abstract;

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
PKC
By biological activity:
PKC Substrate
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,