Neuropeptide widely expressed in the central and peripheral nervous systems and in the endocrine system. Has been shown to regulate numerous physiological and pathological processes through interactions with three G-protein-coupled receptors, GalR1 through GalR3.
Product Details
| Sequence: | H-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-Val-Gly-Asn-His-Arg-Ser-Phe-Ser-Asp-Lys-Asn-Gly-Leu-Thr-Ser-OH |
| |
| Formula: | C139H210N42O43 |
| |
| MW: | 3157.5 |
| |
| CAS: | 119418-04-1 |
| |
| Quantity: | *Sold as net peptide weight. |
| |
| Purity: | ≥98% |
| |
| Appearance: | White to off-white powder. |
| |
| Solubility: | Soluble in water, 0.1% TFA or acetic acid solution. |
| |
| Shipping: | Ambient Temperature |
| |
| Long Term Storage: | -20°C |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
Product Literature References
Human galanin: molecular cloning reveals a unique structure: H.F. Evans & J. Shine; Endocrinology
129, 1682 (1991),
Abstract;
Human galanin: primary structure and identification of two molecular forms: M. Bersani, et al.; FEBS Lett.
283, 189 (1991),
Abstract;
Isolation and primary structure of pituitary human galanin, a 30- residue nonamidated neuropeptide: W.E. Schmidt, et al.; PNAS
88, 11435 (1991),
Abstract;
Galanin in the porcine pancreas: T. Messell, et al.; Regul. Pept.
28, 161 (1990),
Abstract;
Co-existence of galanin and acetylcholine: is galanin involved in memory processed and dementia?: J.N. Crawley & G.L. Wenk; TINS
12, 278 (1989),
Abstract;
Inhibitory action of galanin on gastric acid secretion in pentobarbital-anesthetized rats: W.J. Rossowski & D.H. Coy; Life Sci.
44, 1807 (1989),
Abstract;
Galanin and the endocrine pancreas: B. Ahren, et al.; FEBS Lett.
229, 233 (1988),
Abstract;
Galanin. A selective inhibitor of insulin secretion?: J. Dupré; Pancreas
3, 119 (1988),
Abstract;
Galanin - a newly isolated biologically active neuropeptide: A. Rökaeus; Trends Neurosci. 10, 158 (1987),
Galanin: profile of a new neuropeptide: L.W. Haynes; TIPS 7, 214 (1986), (Review),
