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EGF receptor (human) (651-658) (myristoylated)

Cell permeable PKC inhibitor
 
ALX-155-022-M001 1 mg 58.00 USD
 
ALX-155-022-M005 5 mg 186.00 USD
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Potent, cell permeable and possibly selective inhibitor of protein kinase C (PKC). This product is the N-terminal myristoylated form of Prod. No. ALX-155-021.

Product Specification

Alternative Name:Epidermal growth factor receptor (651-658) (myristoylated), EGFR (651-658) (myristoylated), HER-1 (651-658) (myristoylated)
 
Sequence:Myr-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-OH
 
Formula:C60H117N21O11
 
MW:1308.7
 
Purity:≥97%
 
Appearance:White lyophilized powder.
 
Solubility:Soluble in water.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 

Product Literature References

Inhibition of protein kinase C by N-myristoylated peptide substrate analogs: N.G. Ward & C.A. O'Brian; Biochemistry 32, 11903 (1993), Abstract;
Cyanobacteria secondary metabolites-the cyanotoxins: W.W. Carmichael; J. Appl. Bacteriol. 72, 445 (1992), Abstract;
A novel N-myristylated synthetic octapeptide inhibits protein kinase C activity and partially reverses murine fibrosarcoma cell resistance to adriamycin: C.A. O'Brian, et al.; Invest. New Drugs 9, 169 (1991), Abstract;

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