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ETB receptor antagonist [RES-701-1]

 
ALX-155-018-MC05 0.5 mg 103.00 USD
 
ALX-155-018-M001 1 mg 199.00 USD
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Inhibits selectively the ET-1 binding to the ETB receptor.

Product Specification

Sequence:Gly-Asn-Trp-His-Gly-Thr-Ala-Pro-Asp-Trp-Phe-Phe-Asn-Tyr-Tyr-Trp-OH
(Beta peptide bond between Gly1and Asp9).
 
Formula:C103H115N23O23
 
MW:2043.2
 
Formulation:Lyophilized.
 
Peptide Content:75-90%
 
Purity:≥97% (HPLC)
 
Solubility:Soluble in DMSO (5mg/ml); dilute with 0.6ml distilled water.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 

Product Literature References

J.X. He, et al.; Bioorg. Med. Chem. Lett. 5, 621 (1995),
RES-701-1, a novel and selective endothelin type B receptor antagonist produced by Streptomyces sp. RE-701. I. Characterization of producing strain, fermentation, isolation, physico-chemical and biological properties: Y. Morishita, et al.; J. Antibiot. 47, 269 (1994), Abstract;
Subtypes of endothelin ETA and ETB receptors mediating venous smooth muscle contraction: S.A. Sudjarwo, et al.; BBRC 200, 627 (1994), Abstract;

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For Research Use Only. Not for use in diagnostic procedures.
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