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ETB receptor antagonist [IRL-1038]

 
ALX-155-007-PC05 0.5 mg* 86.00 USD
 
ALX-155-007-P001 1 mg* 174.00 USD
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Antagonist for the ETB receptor with a controversial pattern of activity.

Product Specification

Alternative Name:[Cys11-Cys15]-Endothelin-1 (11-21)
 
Sequence:H-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH
(Disulfide bonds between Cys1-Cys5)
 
Formula:C68H92N14O15S2
 
MW:1409.7
 
Quantity:*Sold as net peptide weight.
 
Purity:≥97%
 
Shipping:Ambient
 
Long Term Storage:-20°C
 

Product Literature References

An endothelin B receptor-selective antagonist: IRL 1038, [Cys11- Cys15]- endothelin-1(11-21): Y. Urade, et al.; FEBS Lett. 342, 103 (1994), Abstract;
Endothelin: progress in pharmacology and physiology: W.G. Haynes, et al.; TIPS 14, 225 (1993), (Review), Abstract;
A potent and specific agonist, Suc-[Glu9,Ala11,15]-endothelin-1(8-21), IRL 1620, for the ETB receptor: M. Takai, et al.; BBRC 184, 953 (1992), Abstract;
An endothelin B receptor-selective antagonist: IRL 1038, [Cys11-Cys15]- endothelin-1(11-21) [retracted in: FEBS Lett 1994 Mar 28;342(1):103]: Y. Urade, et al.; FEBS Lett. 311, 12 (1992), Abstract;

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For Research Use Only. Not for use in diagnostic procedures.
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