Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Big Endothelin-1 (human) (1-38)

Endothelin-converting enzyme substrate
 
ALX-152-001-PC01 0.1 mg* 114.00 USD
 
ALX-152-001-PC05 0.5 mg* 497.00 USD
 
ALX-152-001-P001 1 mg* 808.00 USD
Do you need bulk/larger quantities?
 
Biological precursor of endothelin 1. Cleaved to yield endothelin-1 via the activity of the endothelin-converting enzyme (ECE). Endothelins are endothelium-derived vasoconstrictor peptides.

Product Specification

Alternative Name:Big ET-1 (1-38)
 
Sequence:H-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-Val-Asn-Thr-Pro-Glu-His-Val-Val-Pro-Tyr-Gly-Leu-Gly-Ser-Pro-Arg-Ser-OH
(Disulfide bonds between Cys1-Cys15and Cys3-Cys11)
 
Formula:C189H282N48O56S5
 
MW:4283.0
 
CAS:121014-53-7
 
Quantity:*Sold as net peptide weight.
 
Purity:≥98% (HPLC)
 
Appearance:White to off-white powder.
 
Solubility:1mg/ml soluble in water; also soluble in 0.5% acetic acid.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 

Product Literature References

Putative precursors of endothelin have less vasoconstrictor activity in vitro but a potent pressor effect in vivo: T. Kashiwabara, et al.; FEBS Lett. 247, 73 (1989), Abstract;
Cloning and sequence analysis of cDNA encoding the precursor of a human endothelium-derived vasoconstrictor peptide, endothelin: identity of human and porcine endothelin: Y. Itoh, et al.; FEBS Lett. 231, 440 (1988), Abstract;

Recommend this page

 
Keep in touch

©2017 Enzo Life Sciences, Inc.,