Peptide containing a phosphotyrosyl mimetic. Effective protein tyrosine kinase inhibitor. Inhibits the phosphoinositide 3-kinase (PI(3)K) C-terminal p85 SH2 domain.
Product Specification
| Formula: | C39H57N7O14S |
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| MW: | 880.0 |
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| Purity: | ≥96% (HPLC) |
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| Appearance: | White to off-white powder. |
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| Solubility: | Soluble in water (1mg/ml). |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Peptide is very unstable. |
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Product Literature References
L-O-(2-malonyl)tyrosine: a new phosphotyrosyl mimetic for the preparation of Src homology 2 domain inhibitory peptides: B. Ye, et al.; J. Med. Chem.
38, 4270 (1995),
Abstract;