Amino acid analog of glutamine, uniquely found in green tea. Increases brain serotonin, dopamine and GABA levels and binds to AMPA, kainate and NMDA receptors. Has been shown to exert neuroprotective effects in animal models possibly through its antagonistic effects on group 1 metabotrophic glutamate receptors. Behavioural studies with rats suggest L-Theanine to positiveley affect learning and memory processes. Promotes self-renewal of human embryonic stem cells.
Product Details
Alternative Name: | Nγ-Ethyl-L-glutamine, L-Glutamic acid γ-(ethylamide) |
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Formula: | C7H14N2O3 |
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MW: | 174.20 |
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Source: | Synthetic. |
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CAS: | 3081-61-6 |
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Purity: | ≥98% (Titration) |
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Appearance: | White to off-white solid. |
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Solubility: | Soluble in water (50mg/ml). |
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Shipping: | Blue Ice |
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Long Term Storage: | +4°C |
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Handling: | Protect from moisture. |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Distribution and biosynthesis of theanine in Theaceae plants.: W.W. Deng, et al.; Plant Physiol. Biochem.
48, 70 (2009),
Abstract;
Effects of theanine, a unique amino acid in tea leaves, on memory in a rat behavioral test.: T. Yamada, et al.; Biosci. Biotechnol. Biochem.
72, 1356 (2008),
Abstract;
Theanine and glutamate transporter inhibitors enhance the antitumor efficacy of chemotherapeutic agents.: T. Sugiyama & Y. Sadzuka; Biochim. Biophys. Acta
1653, 47 (2003),
Abstract;
Inhibition by theanine of binding of [3H]AMPA, [3H]kainate, and [3H]MDL 105,519 to glutamate receptors.: T. Kakuda, et al.; Biosci. Biotechnol. Biochem.
66, 2683 (2002),
Abstract;