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Synaptotagmin I polyclonal antibody

 
ADI-VAS-SV008-D 50 µg 161.00 USD
 
ADI-VAS-SV008-F 200 µg 356.00 USD
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Product Specification

Alternative Name:SYT
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to the sequence near the N-terminus of rat Synaptotagmin I.
 
UniProt ID:P21707
 
GenBank ID:X52772
 
Species reactivity:Rat
Xenopus
 
Applications:ICC, IHC (PS), WB
 
Recommended Dilutions/Conditions:Western Blot (1:1,000, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~65kDa by Western blot.
 
Purity Detail:Protein A affinity purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Synaptotagmins (Syt) are membrane-trafficking proteins characterized by an N-terminal transmembrane region, a variable linker, and two C-terminal C2-domains, C2A and C2B. At least twelve Synaptotagamins are expressed in vertebrates and can be found in both vesicular and plasma membranes.
 
VAS-SV008 WB
Western blot analysis: Lane 1: Rat Brain, Lane 2: Mouse Brain, Lane 3: Xenopus Ovary, probed with Synaptotagmin I pAb (Prod. No. ADI-VAS-SV008)
VAS-SV008 IHC
Immunohistochemistry analysis of human colon tissue stained with Synaptotagmin I, pAb at 20µg/ml.
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VAS-SV008 WB VAS-SV008 IHC

Product Literature References

GABAergic innervation organizes synaptic and extrasynaptic GABAA receptor clustering in cultured hippocampal neurons: A.L. De Blas, et al. ; J. Neurosci. 22, 684 (2002), Application(s): ICC using rat samples, Abstract;
Synaptotagmin I is a molecular target for lead: J. Pevsner, et al. ; J. Neurochem. 76, 1724 (2001), Application(s): WB using rat samples, Abstract;

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