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CSP polyclonal antibody

 
ADI-VAP-SV003-E 100 µg 281.00 USD
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Product Specification

Alternative Name:Cysteine String Protein, DnaJC5
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to the sequence near the C-terminus of rat CSP. The sequence is completely conserved in bovine.
 
UniProt ID:P60905
 
GenBank ID:U39320
 
Species reactivity:Mouse, Rat
Bovine, Xenopus
 
Applications:IHC, IP, WB
 
Recommended Dilutions/Conditions:Immunohistochemistry, Immunoprecipitation (0.5µg/ml)
Western Blot (1:2,000, colorimetric)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~34kDa by Western blot.
 
Purity Detail:Immunoaffinity purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Cysteine string protein (CSP) is a 34 kDa rat brain protein localized to the cytoplasmic surface of the synaptic vesicle. CSP is believed to perform similar functions in the assembly of synaptic vesicle proteins which are essential to membrane trafficking.
 
VAP-SV003 WB
Western blot analysis of mouse brain tissue extract, probed with CSP, pAb.
VAP-SV003 IHC
Immunohistochemistry analysis of Xenopus embryonic retina section stained with CSP, pAb.
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VAP-SV003 WB VAP-SV003 IHC

Product Literature References

Clinically early-stage CSPα mutation carrier exhibits remarkable terminal stage neuronal pathology with minimal evidence of synaptic loss: B.A. Benitez, et al.; Acta Neuropathol. Commun. 3, 73 (2015), Application(s): Immunoblotting with human cell lysates, Abstract; Full Text
CRHSP-28 regulates Ca(2+)-stimulated secretion in permeabilized acinar cells: G.E. Groblewski, et al. ; J. Biol. Chem. 276, 28866 (2001), Application(s): WB using rat samples, Abstract;
Cysteine string protein, a DnaJ family member, is present on diverse secretory vesicles: R.H. Scheller, et al. ; Neuropharmacology 34, 1361 (1995), Application(s): WB using rat samples, Abstract;

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