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Membrin polyclonal antibody

 
ADI-VAP-PT049-C 25 µg 108.00 USD
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Product Specification

Alternative Name:GOSR2, golgi SNAP receptor complex member
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to a portion of rat membrin.
 
UniProt ID:O35165
 
GenBank ID:U91539
 
Species reactivity:Human, Mouse, Rat
Bovine, Chicken, Dog, Drosophila, Hamster, Monkey, Porcine, Rabbit, Sheep
 
Applications:IHC (PS), WB
 
Recommended Dilutions/Conditions:Western Blot (2µg/ml, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~27kDa by Western blot.
Cited applications include Immunofluorescence.
 
Purity Detail:Peptide immunoaffinity purified.
 
Formulation:Liquid. In borate buffered saline, pH 8.4, containing 25mM sodium borate, 100mM boric acid, 75mM sodium chloride, 5mM EDTA (disodium salt).
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Membrin, also known as GS27 (Golgi SNARE of 27K), is an integral membrane protein present on the surface of the Golgi apparatus. GS27 is a member of a protein complex that consists of cis-Golgi vesicle receptor syntaxin 5 and GS28, v-SNARE rbet1 and Rsec22, and Rsly1. These complexes are postulated to direct the fusion of ER-derived vesicles with vesicular tubular cluster (VTC), and the fusion of VTCs to form cis-Golgi compartment.
 
Technical Info/Product Notes:Recommended by the Human Protein Atlas Organization for IHC (Ensembl No. ENSG00000108433).
 
VAP-PT049 IHC
Immunohistochemistry analysis of human liver tissue stained with Membrin, pAb at 10µg/ml.
Please mouse over
VAP-PT049 IHC

Product Literature References

Data supporting ER stress response in NG108-15 cells involves upregulation of syntaxin 5 expression and reduced amyloid β peptide secretion: K. Suga, et al.; Data Brief 5, 782 (2015), Application(s): Western blot, Abstract;
ER stress response in NG108-15 cells involves upregulation of syntaxin 5 expression and reduced amyloid β peptide secretion: K. Suga, et al.; Exp. Cell Res. 332, 11 (2015), Application(s): Western Blotting, Abstract;
Proinsulin intermolecular interactions during secretory trafficking in pancreatic β cells: L. Haataja, et al.; J. Biol. Chem. 288, 1896 (2013), Application(s): Immunofluorescence of rat INS1 cells, Abstract; Full Text
Segregation of the Qb-SNAREs GS27 and GS28 into Golgi vesicles regulates intra-Golgi transport: A. Fusella, et al.; Traffic. 14, 568 (2013), Application(s): Western blot using hamster CHO cells, Abstract; Full Text

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