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Dynamin monoclonal antibody (D5)

 
ADI-VAM-SV041-E 100 µg 291.00 USD
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Product Specification

Alternative Name:DNM, DYN
 
Clone:D5
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Recombinant His6-tagged human dynamin.
 
UniProt ID:Q05193 (Dynamin-1), P50570 (Dynamin-2), Q9UQ16 (Dynamin-3)
 
Species reactivity:Human, Mouse, Rat
Bovine, Chicken
 
Applications:Flow Cytometry, IHC, IP, WB
 
Recommended Dilutions/Conditions:Flow Cytometry (10µg/ml)
Immunohistochemistry (1:50, human colon cancer tissue)
Western Blot (0.5µg/ml, colorimetric)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~100kDa by Western blot.
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 0.1mM PMSF and 50% glycerol.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Dynamin is a 100 kDa GTP binding protein that was first identified as a protein able to bind microtubules. To date, three genes have been found to encode Dynamin isoforms. Dynamin 1 is neuronal specific, Dynamin 2 is ubiquitously expressed and Dynamin 3 localizes to testis, brain and lung. Dynamin may mediate vesicle formation by assembling into a ring structure around the necks of invaginated coated pits that may eventually lead to the closure of the neck and formation of vesicles.
 
VAM-SV041-Antibody-Blot
ADI-VAM-SV041 WB
Western blot analysis of Dynamin, mAb (D5) (Prod. No. ADI-VAM-SV041): Lane 1: MW marker, Lane 2: Mouse Brain (Prod. No.: ADI-LYT-MB100), Lane 3: Rat Brain (Prod. No.: ADI-LYT-RB100)
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VAM-SV041-Antibody-Blot ADI-VAM-SV041 WB

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