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Membrin monoclonal antibody (4HAD6)

 
ADI-VAM-PT046-D 50 µg 188.00 USD
 
ADI-VAM-PT046-F 200 µg 399.00 USD
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Product Specification

Alternative Name:GOSR2, golgi SNAP receptor complex member
 
Clone:4HAD6
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Recombinant rat Membrin protein with a His tag.
 
UniProt ID:O35165
 
Species reactivity:Human, Rat
Chicken, Dog, Hamster, Monkey, Porcine, Rabbit
 
Applications:ICC, IHC (PS), WB
 
Application Notes:Detects a band of ~27kDa by Western blot.
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 0.1MM PMSF and 50% glycerol.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Membrin, also known as GS27 (Golgi SNARE of 27K), is an integral membrane protein present on the surface of the Golgi apparatus. GS27 is a member of a protein complex that consists of cis-Golgi vesicle receptor syntaxin 5 and GS28, v-SNARE rbet1 and Rsec22, and Rsly1. These complexes are postulated to direct the fusion of ER-derived vesicles with vesicular tubular cluster (VTC), and the fusion of VTCs to form cis-Golgi compartment.
 
VAM-PT046 WB
Western blot analysis of VAM-PT046: Lane 1: MW marker, Lane 2: HeLa, Lane 3: PC-12, Lane 4: RK13, Lane 5: Vero.
VAM-PT046 IHC
Immunohistochemistry analysis of human pancreas tissue stained with Membrin, mAb (4HAD6) at 20µg/ml.
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VAM-PT046 WB VAM-PT046 IHC

Product Literature References

Identification of a human orthologue of Sec34p as a component of the cis-Golgi vesicle tethering machinery: V.V. Lupashin, et al. ; J. Biol. Chem. 276, 22810 (2001), Application(s): ICC using human samples, Abstract;

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