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SAP102 monoclonal antibody (7D3 monoclonal antibody 119)

 
ADI-VAM-PS006-D 50 µg 184.00 USD
 
ADI-VAM-PS006-F 200 µg 360.00 USD
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Product Specification

Alternative Name:Synapse-associated protein 102, Disks large homolog 3
 
Clone:7D3, mAb 119
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Recombinant rat SAP102 (N-terminal fragment).
 
UniProt ID:Q62936
 
GenBank ID:U50147
 
Species reactivity:Mouse, Rat
 
Applications:IHC, IP, WB
 
Recommended Dilutions/Conditions:Western Blot (1:1,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~102kDa by Western blot.
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Synapse-associated proteins SAP97 and SAP102 display extensive sequence homology to the PSD 95 family of proteins that facilitate ion channel clustering at synaptic terminals. In addition to the CNS, SAP97 is also detected at the basal lateral membrane between a variety of epithelial cells. SAP102 associates with NMDA receptors through the C-terminal NR2B subunit of the receptor. The N-terminal SAP97 PDZ domain mediates its interaction with the synaptic ras-GTPase activating protein SynGAP.
 
VAM-PS006 WB
Western blot analysis of SAP102: Lane 1: MW marker, Lane 2: Rat Nucleus Accumbens, Lane 3: Rat Nucleus Accumbens.
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VAM-PS006 WB

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