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Glutathione NEM monoclonal antibody (8.IGSH)

ADI-SPA-540-C 25 µg 130.00 USD
ADI-SPA-540-E 100 µg 304.00 USD
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Product Specification

Alternative Name:HAGHL, hydroxyacylglutathione hydrolase-like
Immunogen:Thiol-modified glutathione conjugated to KLH.
Species reactivity:Mammalian
Applications:ELISA, Flow Cytometry, ICC
Formulation:Liquid. In PBS, pH 7.2, containing 0.1mM PMSF.
Handling:Avoid freeze/thaw cycles.
Shipping:Shipped on Blue Ice
Long Term Storage:-20°C
Scientific Background:Glutathione, a major intracellular non-protein thiol, protects against free radical damage by providing reducing equivalents for several key antioxidant enzymes. In addition, glutathione acts as a scavenger of hydroxyl radicals and nascent oxygen. Elevated glutathione levels are associated with a reduced rate of illness, higher levels of self-rated health, lower cholesterol, lower body mass index, and lower blood pressure among the elderly. Glutathione provides a primary defense system for the removal of oxidants in the brain. Studies have revealed a correlation between low glutathione levels and damage to neurons that manufacture dopamine, suggesting a link to Parkinson's disease.

Product Literature References

Glutathione distribution in normal and oxidatively stressed cells: D.A. Lawrence, et al. ; Exp. Cell Res. 285, 14 (2003), Application(s): EM using human samples, Abstract;
Phospholipid metabolism of lymphocytes with inhibited glutathione synthesis using L-buthionine-S,R-sulfoximine: D.A. Lawrence, et al. ; Free Radic. Biol. Med. 18, 709 (1995), Application(s): Flow using human samples, Abstract;

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