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HSP40/Hdj1 polyclonal antibody (DyLight™ 488 conjugate)

 
ADI-SPA-400-488-D 50 µg 205.00 USD
 
ADI-SPA-400-488-F 200 µg 443.00 USD
Do you need bulk/larger quantities?
 

Product Specification

Alternative Name:Heat shock protein 40
 
Host:Rabbit
 
Immunogen:Recombinant human Hsp40.
 
UniProt ID:P25685
 
GenBank ID:D49547
 
Species reactivity:Human, Mouse, Rat
Beluga, Bovine, Chicken, Dog, Fish, Guinea pig, Hamster, Monkey, Mussel, Porcine, Rabbit, Scallop, Sheep, Xenopus
 
Applications:Flow Cytometry
 
Recommended Dilutions/Conditions:Flow Cytometry (1:20)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Protein A affinity purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 0.09% sodium azide.
 
Handling:Avoid freeze/thaw cycles. Protect from light.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:+4°C
 
Scientific Background:Hsp40/Hdj1 is a cytosolic co-chaperone belonging to the class DnaJ, named after its homolog in E. coli. Hsp40 functions in protein folding by binding nascent peptides and unfolded substrates and facilitating substrate interaction with Hsp70. Binding of Hsp40 to Hsp70 increases Hsp70 ATP hydrolysis and substrate binding, which is reversed by the action of nucleotide exchange factors (GrpE in E. coli). Repeated cycles of Hsp40/Hsp70 peptide binding and ATP hydrolysis prevent premature folding and aggregation, promoting protein maturation throughout the cell.
 
SPA-400-488 FC
Flow cytometry analysis of 106 Jurkat cells stained using HSP40 mAb (Hdj1), DyLight™ 488 Conjugate at a concentration of 50µg/ml.
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SPA-400-488 FC

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