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[pSer45]αB-Crystallin, pAb

 
ADI-SPA-226-D 50 µg 190.00 USD
 
ADI-SPA-226-F 200 µg 370.00 USD
 

Product Specification

Alternative Name:CRYA, HspB, sHSP, HSPB5, small heat shock protein
 
Purity Detail:Affinity purified.
 
Formulation:Liquid. In 0.1M sodium phosphate buffer, pH 7.0, containing 1.5% BSA and 0.1% sodium azide.
 
Immunogen:Synthetic peptide corresponding to a portion of human αB-crystallin phosphorylated at Ser45.
 
Source/Host:From rabbit.
 
Specificity:Recognizes human, mouse, rat, bovine, chicken, dog, guinea pig, hamster, monkey, pig, rabbit, scallop and Xenopus αB-crystallin. Detects a band of ~22kDa by Western blot.
 
Application:Immunoprecipitation
Western Blot (1:500, ECL)
Optimal conditions must be determined individually for each application.
 
Long Term Storage:-20°C
 
Miscellaneous/General:Alpha-crystallins, which are part of the small Heat shock family members, are major water-soluble proteins present in the lens of the mammalian eye. Phosphorylation of serine residues which occurs during development and in response to stress, is intimately linked with its function. Chaperone activity requires, and is modulated by, oligomerization and is limited to binding unfolded intermediates to prevent irreversible aggregation.
 
SPA-226 WB
Western blot analysis of Crystallin alpha-B (pSer45): Lane 1: MW marker, Lane 2: alpha-B1 Crystallin Protein (phospho), Lane 3: alpha-B2 Crystallin Protein (non-phospho)
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SPA-226 WB
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