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Mn SOD polyclonal antibody

 
ADI-SOD-110-D 50 µg 184.00 USD
 
ADI-SOD-110-F 200 µg 389.00 USD
 
ADI-SOD-110-J 1 mg 1,392.00 USD
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Product Specification

Alternative Name:Manganese superoxide dismutase
 
Host:Rabbit
 
Immunogen:Human Mn SOD protein.
 
UniProt ID:P04179
 
Gene/Protein Identifier:NP_000627 (RefSeq)
 
Species reactivity:Human, Mouse, Rat
Bovine, Dog, Guinea pig, Hamster, Monkey, Rabbit, Sheep, Xenopus
 
Applications:IHC, WB
 
Recommended Dilutions/Conditions:Western Blot (1:1,000, colorimetric)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~25kDa by Western blot.
 
Purity Detail:Protein A affinity purified.
 
Formulation:Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:SOD (Superoxide dismutase) is responsible for the elimination of cytotoxic active oxygen by catalyzing the dismutation of the superoxide radical to oxygen and hydrogen peroxide. There are three SOD isoenzymes in mammalian cells, they are: EC SOD (extracellular SOD), Cu/Zn SOD (copper and zinc-containing SOD) and Mn SOD (manganese-containing SOD).
 
SOD-110 WB
Western blot analysis of Mn SOD: Lane 1: MW Marker, Lane 2: HeLa Cell Lysate, Lane 3: Mouse Brain Tissue Extract, Lane 4: Rat Brain Tissue Extract
SOD-110 IHC
Immunohistochemistry analysis of human skeletal muscle tissue stained with Mn SOD, pAb at 10µg/ml.
Please mouse over
SOD-110 WB SOD-110 IHC

Product Literature References

Cerebrovascular endothelial dysfunction induced by mercury exposure at low concentrations: G.A. Wiggers, et al.; Neurotoxicology 53, 282 (2016), Application(s): Western blot, Abstract;
Effect of mitochondrial fission inhibition on C2C12 differentiation: D. Bloemberg, et al.; Data Brief 7, 634 (2016), Application(s): Immunoblotting, Abstract; Full Text
MDM4/HIPK2/p53 cytoplasmic assembly uncovers coordinated repression of molecules with anti-apoptotic activity during early DNA damage response: F. Mancini, et al.; Oncogene 35, 228 (2016), Application(s): Western Blot, Abstract; Full Text
Resistance training and redox homeostasis: Correlation with age-associated genomic changes: I. Dimauro, et al.; Redox Biol. 10, 34 (2016), Application(s): Western blot, PBMCs, Abstract; Full Text
The effect of chronic exposure to high palmitic acid concentrations on the aerobic metabolism of human endothelial EA.hy926 cells: I. Broniarek, et al.; Pflugers Arch. 468, 1541 (2016), Application(s): Determination of protein levels via immunoblotting, Abstract;
The effect of R-(-)-deprenyl administration on antioxidant enzymes in rat testis: F. Horvathova, et al. ; Eur. J. Pharmacol. 788, 21 (2016), Application(s): Immunohistochemistry, Abstract;
Alcohol and High Fat Induced Chronic Pancreatitis: TRPV4 Antagonist Reduces Hypersensitivity: L. Zhang, et al.; Neuroscience 311, 166 (2015), Application(s): Immunohistochemical localization of MnSOD in pancreas tissue, Abstract;
Antioxidant supplementation accelerates cachexia development by promoting tumor growth in C26 tumor-bearing mice: M. Assi, et al.; Free Radic. Biol. Med. 91, 204 (2015), Application(s): Western blot, Abstract;
Cytotoxic and genotoxic effects mediated by M2 muscarinic receptor activation in human glioblastoma cells: M. Di Bari, et al.; Neurochem. Int. 90, 261 (2015), Application(s): Western Blot, Abstract;
Effects of deletion of the transcription factor Nrf2 and benzo [a]pyrene treatment on ovarian follicles and ovarian surface epithelial cells in mice: J. Lim, et al.; Reprod. Toxicol. 58, 24 (2015), Application(s): Immunoblotting for SOD2 in ovarian extracts , Abstract;
Effects of Exercise and Alpha-Lipoic Acid Supplementation on Brain Tissue Protection in Experimental Diabetes: Z. Pündük; (2015), (PhD thesis), Application(s): Western assay, Full Text
The beneficial effects of exercise on cartilage are lost in mice with reduced levels of ECSOD in tissues: K.M. Pate, et al.; J. Appl. Physiol. (1985) 118, 760 (2015), Application(s): Western Blotting, Abstract; Full Text
Glutathione depletion in antioxidant defense of differentiated NT2-LHON cybrids: E. Kirches, et al. ; Neurobiol. Dis. 25, 536 (2007), Application(s): WB using human cell lysates, Abstract;
The role of peroxisomal ABC transporters in the mouse adrenal gland:the loss of Abcd2 (ALDR), Not Abcd1 (ALD), causes oxidative damage: J. Powers, et al. ; Lab. Invest. 87, 261 (2007), Application(s): IHC using mouse tissue, Abstract;
TLR4-mediated survival of macrophages is MyD88 dependent and requires TNF-α autocrine signalling: E. Lombardo, et al. ; J. Immunol. 178, 3731 (2007), Application(s): WB using mouse cell lysates, Abstract;
Time sequence of maturation of dystrophic neurites associated with Abeta deposits in APP/PS1 transgenic mice: L. Pradier, et al. ; Exp. Neurol. 184, 247 (2003), Application(s): IHC using mouse samples, Abstract;
Heme oxygenase-1-derived carbon monoxide requires the activation of transcription factor NF-kappa B to protect endothelial cells from tumor necrosis factor-alpha -mediated apoptosis: M.P. Soares, et al. ; J. Biol. Chem. 277, 17950 (2002), Application(s): WB using human & bovine samples, Abstract;

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