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EC SOD polyclonal antibody

 
ADI-SOD-106-D 50 µg 161.00 USD
 
ADI-SOD-106-F 200 µg 334.00 USD
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Product Specification

Alternative Name:Superoxide Dismutase, SOD3
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to a portion of EC SOD. The sequence is completely conserved in human, mouse, rat and rabbit.
 
UniProt ID:P08294
 
Species reactivity:Human, Mouse, Rat
 
Applications:WB
 
Recommended Dilutions/Conditions:Western Blot (1:1,000, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~35-40kDa (glycosylation dependent) by Western blot.
 
Purity Detail:Protein A affinity purified.
 
Formulation:Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:SOD (Superoxide dismutase) is responsible for the elimination of cytotoxic active oxygen by catalyzing the dismutation of the superoxide radical to oxygen and hydrogen peroxide. There are three SOD isoenzymes in mammalian cells, they are: EC SOD (extracellular SOD), Cu/Zn SOD (copper and zinc-containing SOD) and Mn SOD (manganese-containing SOD).
 
SOD-106 WB
Western blot analysis of EC SOD: Lane 1: MW Marker, Lane 2: Rat Lung Tissue Extract, Lane 3: Mouse Lung Tissue Extract, Lane 4: Human EC SOD Protein.
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SOD-106 WB

Product Literature References

Cerebrovascular endothelial dysfunction induced by mercury exposure at low concentrations: G.A. Wiggers, et al.; Neurotoxicology 53, 282 (2016), Application(s): Western blot, Abstract;
MAPK pathway activation by chronic lead-exposure increases vascular reactivity through oxidative stress/cyclooxygenase-2-dependent pathways: M.R. Simões, et al.; Toxicol. Appl. Pharmacol. 283, 127 (2015), Application(s): Western Blotting, Abstract;
Hydrocortisone normalizes phosphodiesterase-5 activity in pulmonary artery smooth muscle cells from lambs with persistent pulmonary hypertension of the newborn: M. Perez, et al.; Pulm. Circ. 4, 71 (2014), Application(s): WB using fetal lamb pulmonary arterial smooth muscle cell (FPASMC) lysates, Abstract; Full Text
Low mercury concentrations cause oxidative stress and endothelial dysfunction in conductance and resistance arteries: M. Salaices, et al. ; Am. J. Physiol. Heart Circ. Physiol. 295, H1033 (2008), Application(s): WB using rat tissue, Abstract;

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