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Biliverdin Reductase (rat), (recombinant)

ADI-OSP-400-B 20 µg 127.00 USD
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Product Specification

Alternative Name:BLVR
Source:Produced in E. coli.
UniProt ID:P46844
GenBank ID:M81681
Formulation:Liquid. In 0.01M TRIS-HCl, pH 8.0, containing 1mM EDTA.
Purity:≥95% (SDS-PAGE; Western blot)
Purity Detail:Unpurified lysate.
Applications:IHC, WB
Application Notes:Western blot control.
Shipping:Shipped on Dry Ice
Long Term Storage:-80°C
Scientific Background:The phosphoprotein BVR (Biliverdin Reductase) is an oxireductase which catalyzes the reduction of the gamma-meso bridge of Biliverdin to Bilirubin. BVR is unique among all enzymes characterized to date because BVR has dual pH/dual cofactor requirements. The reductase is highly conserved in its primary structure and molecular properties and uses NADH in the acidic range (peak activity at pH~6.7), whereas NADPH is utilized in the basic range (peak activity at pH ~8.7).

Product Literature References

Enhancing the anti-inflammatory activity of chalcones by tuning the Michael acceptor site: H. Rucker, et al.; Org. Biomol. Chem. 13, 3040 (2016), Application(s): Cell culture, Abstract; Full Text
The Cytoprotective Effects of E-α-(4-Methoxyphenyl)-2',3,4,4'-Tetramethoxychalcone (E-α-p-OMe-C6H4-TMC)-A Novel and Non-Cytotoxic HO-1 Inducer: K.B. Kaufmann, et al.; PLoS One 10, e0142932 (2015), Application(s): Part of protease inhibitor cocktail, Abstract; Full Text

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