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United States 

Cysteine monoclonal antibody (6B4)

 
ADI-OSA-800-E 100 µg 250.00 USD
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Product Specification

Clone:6B4
 
Host:Mouse
 
Isotype:IgG2a
 
Species reactivity:Species independent
 
Applications:ELISA, IHC, IP, WB
 
Recommended Dilutions/Conditions:Western Blot (1:1,000, non-reducing)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In PBS containing 0.01% sodium azide.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:The formation of protein-cysteine adducts, or cysteinylation, is a post-translational protein modification known to modify inherent protein binding properties. Cysteinylation is known to affect the presentation of antigenic peptide epitopes on MHC molecules, regulating the immune response to tumor antigens and contributing to autoimmune diseases including type I diabetes. Cysteinylation of the potentially oncogenic protein kinase C (PKC) isozymes epsilon and gamma has been shown to regulate inactivation of their enzymatic activity, at the same time stimulating the pro-apoptotic function of PKC delta, making isozyme-specific PKC regulators an attractive target for the treatment of proliferative diseases such as cancer.
 

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Cysteine
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