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NQO1 monoclonal antibody (A180)

 
ADI-OSA-700-D 50 µg 215.00 USD
 
ADI-OSA-700-F 200 µg 378.00 USD
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Product Specification

Alternative Name:NADPH:Quinone Oxidoreductase
 
Clone:A180
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Recombinant human NQO1.
 
UniProt ID:P15559
 
Gene/Protein Identifier:NP_000894.1 (RefSeq)
 
Species reactivity:Human
 
Applications:IHC (PS), WB
 
Recommended Dilutions/Conditions:Western Blot (1µg/ml AP, 1µg/ml ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~31kDa by Western blot.
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:NAD(P)H:quinone oxidoreductase (NQO1) is a flavoprotein which catalyzes the two-electron reduction of quinones. NQO1 plays a role both in the detoxification of phenolic metabolites as well as the bioactivation of many anti-tumor quinones. Its activity can be elevated in human tumors, including colon, breast, lung, and brain carcinomas.
 
ADI-OSA-700 IHC1
IHC Analysis: Human brain, cerebellum tissue stained with NQO1, mAb (A180) at 10µg/ml.
ADI-OSA-700 IHC2
IHC Analysis: Human breast tissue stained with NQO1, mAb (A180) at 10µg/ml.
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ADI-OSA-700 IHC1 ADI-OSA-700 IHC2

Product Literature References

Ethanol Extract of Cirsium japonicum var. ussuriense Kitamura Exhibits the Activation of Nuclear Factor Erythroid 2-Related Factor 2-dependent Antioxidant Response Element and Protects Human Keratinocyte HaCaT Cells Against Oxidative DNA Damage: O.K. Yoo, et al.; J. Cancer Prev. 21, 66 (2016), Application(s): Western blot, Abstract; Full Text

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