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APP polyclonal antibody

ADI-NBA-102-E 100 µg 385.00 USD
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Product Specification

Alternative Name:Amyloid A4 protein, Amyloid protein
Immunogen:Synthetic peptide corresponding to aa 737-751 of human APP or aa 85-99 of human C99 (a fragment generated by β-secretase cleavage). The sequence of this peptide is completely conserved in mouse and rat APP.
UniProt ID:P05067
Species reactivity:Human, Mouse, Rat
Applications:IHC, WB
Recommended Dilutions/Conditions:Western Blot (1µg/ml, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Immunohistochemistry
Western Blot (1µg/ml, ECL)
Optimal conditions must be determined individually for each application.
Purity Detail:Peptide affinity purified.
Formulation:Liquid. In PBS containing 0.02% sodium azide.
Shipping:Blue Ice Not Frozen
Long Term Storage:+4°C
Scientific Background:Deposition of APP (Amyloid A4 protein) precursor intraneuronally as neurofibrillary tangles, extracellularly as plaques, and in blood vessels, is characteristic of both Alzheimer's disease and aged Down's Syndrome. There are five forms of APP: APP395, APP563, APP695, APP751, and APP770. They are produced by alternative splicing of the APP gene. APP695 is the most predominant form in neuronal tissue while APP751 is the predominant form found elsewhere.
NBA-102 WB
Western blot analysis of APP in mouse (M) and rat (R) brain tissue lysates with APP antibody at 2µg/ml.
Immunohistochemistry analysis of rat brain using APP antibody at 2µg/ml.
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NBA-102 WB NBA-102 IHC

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