| ADI-NBA-102-E | 100 µg | 485.00 USD |  |
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| Alternative Name: | Amyloid A4 protein, Amyloid protein |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to aa 737-751 of human APP or aa 85-99 of human C99 (a fragment generated by β-secretase cleavage). The sequence of this peptide is completely conserved in mouse and rat APP. |
| UniProt ID: | P05067 |
| Species reactivity: | Human, Mouse, Rat |
| Applications: | IHC, WB |
| Recommended Dilutions/Conditions: | Western Blot (1µg/ml, ECL) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Application Notes: | Immunohistochemistry Western Blot (1µg/ml, ECL) Optimal conditions must be determined individually for each application. |
| Purity Detail: | Peptide affinity purified. |
| Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
| Shipping: | Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | Deposition of APP (Amyloid A4 protein) precursor intraneuronally as neurofibrillary tangles, extracellularly as plaques, and in blood vessels, is characteristic of both Alzheimer's disease and aged Down's Syndrome. There are five forms of APP: APP395, APP563, APP695, APP751, and APP770. They are produced by alternative splicing of the APP gene. APP695 is the most predominant form in neuronal tissue while APP751 is the predominant form found elsewhere. |
| Regulatory Status: | RUO - Research Use Only |
